Colloquium d'informatique de l'UPMC – Sorbonne Universités
Alessandra Carbone, UPMC Sorbonne Universités

Tuesday 14 April 2015 at 18:00
Location: Amphi 15, Université Pierre et Marie Curie (Jussieu Campus)


Alessandra Carbone is Professor of Computer Science at UPMC and she has led the Analytical Genomics team since 2003. She is the director of the Laboratory of Computational and Quantitative Biology, created in January 2009 by CNRS and UPMC with the aim of developing an interdisciplinary working environment made of several groups of theoreticians and experimentalists interested in bioinformatics and modeling of complex biological systems, systems biology, population genetics.

Alessandra Carbone received the Prix Joliot-Curie in 2010 from the Ministère de la Recherche et de l’Enseignement Supérieur and from the EADS Foundation, and she was distinguished in 2012 with the Grammaticakis-Neuman Prize of the Académie des Sciences for “Integrative Biology”. Since 2013 she is a senior member of the Institut Universitaire de France.

Colloquium: The new era of biology is computational

Biology entered a new era, with bioinformatics producing biological data that are impossible nowadays to obtain with wet experiments. Soon scientists and clinicians will use new DNA technologies to detect mutations driving cancer and other diseases, identify new strains of pathogens, map the physiological effects of the microbial communities residing in our organs, track subtle changes in our immune repertoire, predict drug response, and make innumerable other contributions to our health and knowledge of complex biological systems. The scale and complexity of the data will vastly exceed anything the biological and medical community has faced before. Tackling these questions with advanced engineering, new computer algorithms and novel computational approaches is a challenge that will lead to revolutionize biology and medicine through deeper, ubiquitous use of DNA information. Among different examples, we shall present a computational approach to protein-protein interactions that we developed within a project on neuromuscular diseases. The project demands a high computational power to test billions of interactions, it run on the machines of the World Community Grid for more than 3 years, and provided a huge amount of information on the interaction of human proteins. High Performance Computing helped to obtain an unprecedented amount of information on protein-protein interactions between real partners but also, and most importantly, between non-partners.

Other information

There will be a cocktail at 17:15, in front of Amphi 15.

Amphi 15
Université Pierre et Marie Curie (Jussieu Campus)
4, place Jussieu
Paris Vème (métro Jussieu)

How to reach Université Pierre et Marie Curie (Jussieu campus)..

Electronic access:

Contact: Fabien Tarissan

Steering committee

Marcin Detyniecki
Jean-Charles Faugère
Bertrand Granado
Mathieu Jaume
Nicolas Maudet
Marc Shapiro
Fabien Tarissan

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All the offline videos

Year 2015 – 2016

Isabelle Collet, 24 November 2015

Year 2014 – 2015

Andy Tanenbaum, 28 October 2014
MINIX 3: A Reliable and Secure Operating System

Manuel Silva, 25 November 2014
Fluidization of discrete event models or a marriage between the discrete and the continuous

Serge Abiteboul, 24 February 2015
Toward personal knowledge bases

Alessandra Carbone, 14 April 2015
The new era of biology is computational

Silvio Micali, 26 May 2015

Year 2013 – 2014

Gilles Dowek, 22 October 2013
Are formal methods the future of air traffic control? (Is there an autopilot on board?)

Tony Hoare, 26 November 2013
Laws of concurrent system design

Vint Cerf, 4 March 2014
On the Preservation of Digital Information

Claude Berrou, 25 March 2014
L'information mentale

David Patterson, 6 May 2014
Myths about MOOCs and Software Engineering Education

Jeannette Wing, 20 May 2014
Toward a Theory of Trust in Networks of Humans and Computers

Donald Knuth, 17 June 2014
Computer Science: All Questions Answered

Year 2012 – 2013

Gérard Berry, 24 October 2012
Le temps et les événements en informatique

Georges Gonthier, 27 November 2012
Le génie mathématique, du théorème des quatre couleurs à la classification des groupes

Stuart Russell, 22 January 2013
Unifying logic and probability: A "New Dawn" for Artificial Intelligence?

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The multicore evolution and operating systems

Robert Sedgewick, 23 May 2013
Taking Education Online: A Unique Opportunity for the New Millenium

Camille Couprie, Mathilde Noual and Mathieu Feuillet, 25 June 2013
Espoirs : Winners of the 2012 Gilles Kahn prize

Year 2011 – 2012

Leslie Lamport, 28 June 2012
What is computation?